Meet the Team

We are the imaging software people.

Duane Lawrence

Mirada Medical Chairman, Duane Lawrence, brings with him successful runs leading both high-growth HealthTech SMEs, mid-market publicly traded global technology and service businesses across five continents. A 30-year veteran of the healthcare industry and a US and UK citizen based in the UK, Duane has specialised in building and developing strong teams, recognising emerging opportunities in markets and building programmes and products to successfully fill those opportunities since 2003.

From February 2015 to June 2017, Duane was Managing Director at EMIS Health, the global HealthTech software and services business. Prior to that, Duane was the CEO of InferMed, having joined the Board in May 2007, leading it through to its successful trade exit in 2015.

Prior to this, Duane was GM of Misys Healthcare Systems International Ltd, with responsibility for the company’s operations outside of North America.
A business and finance graduate of the University of Notre Dame in the US, Duane’s successful track record of global commercial leadership is now being shared with HealthTech SMEs and mid-market companies through advisory and NED roles.

Gene Saragnese

Having served as Mirada Chairman since 2015 for over 4 years, Gene Saragnese remains a member of the Board. He was CEO of Philips Imaging Systems from April 2009 until May 2015 and prior to joining Philips, Mr. Saragnese served as GE Healthcare’s Vice President and General Manager of Molecular Imaging and Computed Tomography. He previously served as Chief Technology Officer for GE Healthcare. In this role, Mr. Saragnese led Global Product Development Engineering and Component Operations around the world, including Corporate Research sites in New York, China, India, and Germany. He has also served as General Manager for GE Medical Systems’ Global MRI business and the leader for GE Medical Systems’ Global MRI Engineering organization. Prior to his career in healthcare, Mr. Saragnese held management roles with GE, RCA, Martin Marietta and Lockheed Martin in the aerospace industry. He is a graduate of Rutgers College of Engineering in New Jersey.

Hugh Bettesworth

Hugh Bettesworth has worked in the software industry for over twenty-four years, the last twenty in medical software and digital health. He joined Mirada Medical in 2001 and led a management buyout from Siemens in 2009 which re-established Mirada’s independent status. This independence provided the platform for the innovative software developments that have resulted in Mirada’s subsequent growth and leading technical position today. Since 2009, Mirada has experienced 10-fold growth and the company’s advanced software technologies have been deployed in around 2000 cancer treatment centres worldwide.

David Gudgin

David Gudgin qualified as a management accountant with ICL before spending 3 years at the BBC. In 1999 he joined 3i as an investor in European technology based in London and Amsterdam. In 2002 he moved to Foursome Investments (now Frog Capital) as the lead investor of two funds, an environmental technology fund and a later stage development capital fund. David joined Close Ventures in 2005 and became a partner in Albion Ventures in 2009. David has a BSc in Economics from Warwick University.

Sam Gray

Sam joined Apposite Capital in 2007. He has been particularly involved in all of Apposite’s healthcare services and health IT investments and served on portfolio Boards in both the US and Europe. In addition to Mirada Medical, Sam currently serves on the Board of Medical Imaging Partnership, MC Care Holdings, Summit Medical, Swanton Care and was a Board Director of CancerPartnersUK, By the Bridge, SureCalm and WellPartner. Sam has been involved in deal-making in the healthcare sector since 2000 when he joined Deutsche Bank’s mergers and acquisitions practice, working with a number of multinational clients on corporate divestitures and acquisitions, including public takeovers and leveraged buy-outs. Sam then joined the Business Development team at Belgian pharmaceutical company, UCB, where he was instrumental in global product licensing and M&A, including UCB’s $2.7bn acquisition of the UK public biotech company, Celltech. Sam has a first degree in Natural Sciences and a masters degree in Chemistry from Cambridge University, as well as an MBA from Harvard Business School.

Seb Jantet

Seb Jantet, Mirada’s Chief Financial and Operations Officer has over 25 years of experience in finance, both in the public and private markets. Most recently he was Chief Financial Officer of Induction Healthcare PLC, during which time he steered the company through an AIM IPO, raising just under £17m from investors. Prior to that he was Chief Financial officer of DrugDev Inc, which he joined in 2013 and was part of the team that executed a buy and build strategy in the clinical trials technology market, ultimately culminating in a successful exit to IQVIA in 2017. Seb also spent 22 years working in the City, 11 years of which working at Investec as a top-ranked healthcare analyst and headed up the healthcare equity research team. Prior to that, he worked 4 years for KPMG working in corporate finance. Seb is a qualified accountant, a member of the Institute of Chartered Accountants of England and Wales and has a BA in French and Politics from the University of East Anglia. He is also a non-executive director of Elizabeth Finn Homes Limited.

Hugh Bettesworth

Chief Executive


Mark Gooding

Chief Scientist

Sarah Bond

Chief Product Officer

Anna Griffin

Head of Finance, UK HR and Admin

Peter Bannister

Chief Customer Success Officer

Seb Jantet

Chief Financial and Operations Officer

Neil Graham

Chief Technology Officer

Prof. Amato J. Giaccia – Chair

Dr. Amato J. Giaccia obtained his Ph.D. in Pathology/Molecular Biology from the University of Pennsylvania in Philadelphia.  He is currently the Director of the MRC and CRUK funded Institute of Radiation Oncology at Oxford University in the UK.  He is also Professor Emeritus at Stanford University. At Stanford, he was Professor of Radiation Oncology, Associate Chair for Research & Director of the Division of Radiation & Cancer Biology in the Department of Radiation Oncology.  He also was the Director of Basic Science at the Stanford Cancer Institute and headed the Radiation Biology Program in Stanford’s Cancer Center.  He was awarded an American Cancer Society Junior Faculty Research Award and the Michael Fry Award from the Radiation Research Society for his outstanding contributions on understanding the molecular mechanisms of resistance promoted by the tumor microenvironment.  Additionally, he was the recipient of the 2013 ASTRO Gold Medal.  In 2015, he was awarded an NIH R35 Outstanding Investigator Award and was inducted into the National Academy of Medicine.  He co-authored the sixth, seventh & eighth editions of the textbook, “Radiation Biology for the Radiologist,” with Professor Eric Hall from Columbia.  In addition, he also held the “Jack, Lulu and Sam Willson Professorship in Cancer Biology” in the Stanford University School of Medicine.

Prof. Carlo Greco

Since 2011 Prof. Greco is the incumbent Director of Clinical Research at the Champalimaud Centre for the Unknown (CCU), a translational cancer research institute based in Lisbon. With his team, he has conduced several research studies of extreme hypofractionation and single dose radiation therapy in limited oligometastatic disease  with PET/CT confirmation of long-term complete response in over 90% of lesions treated with SDRT. In 2019 his research in the field of oligometastatic disease culminated in the identification of patients that will most likely benefit from ablative treatment based on pre-treatment clinical and metabolic parameters derived from PET scanning, thus improving optimization of resources and treatment cost-effectiveness.  He is also actively engaged in the management of early stage primary disease with cutting-edge technology and investigator–driven clinical studies using advanced organ motion mitigation techniques and target tracking in various disease settings such as lung and prostate cancer. In prostate cancer, in particular, he has developed an innovative technique that enables the delivery of a single ablative dose of radiation as a viable and non-invasive alternative to surgery. Preliminary results of a randomized clinical study comparing the established five session regimen versus a single ablative exposure in localized prostate cancer  have been presented at international meetings. He is currently involved in the introduction  of AI as a tool to improve accuracy in target volume definition and to predict likelihood of response to treatment thereby permitting identification of patients who may require further treatment.


Dr. Dan Fass

I have thirty-five years clinical experience in Radiation Oncology and was part of the pioneering team that developed both 3D RT and IMRT at Memorial Sloan Kettering Cancer Center. I later brought this technology to community hospitals in the New York area.

Recognizing the global need for access to state of the art radiation therapy services I was chosen as CEO for Princeton Healthcare Alliance. We are opened and manage a radiation oncology facility in Kazakhstan and consult through Central Asia, the Commonwealth of Independent States, GCC countries and Africa. Our team has extensive experience in the design, finance and operation of multi-speciality healthcare facilities.

We work with government ministries, lenders and providers to find site specific cost-effective solutions to benefit patients who would otherwise lack appropriate treatment.

We partner with companies that bring new technology to improve outcomes in the US market, offering practical solutions including AI and ML, working with both major academic institutions and small community practices to enhance value across the enterprise

Dr. Penny Kechagioglou

Dr Penny Kechagioglou is the Chief Medical Officer at GenesisCare UK and has joined the company in February 2018.  She is responsible for providing clinical leadership to the UKLT, driving innovation and research with the support of the clinical leaders forum and the clinical reference groups. In collaboration with the UKLT, she is leading the GenesisCare UK quality framework to ensure compliance and a culture of continuous Quality Improvement.

Dr Kechagioglou has an active public and private practice as a Consultant Clinical Oncologist, with a specialist interest in Breast cancer, Acute Oncology and Clinical Innovations. She has served as Clinical Governance Lead in the NHS, Vice Chair and member of NHS Research Ethics Committees and as member of the NICE Health Technology Assessment Committee. She is also a Specialist Advisor for the Care Quality Commission and the Healthcare Ombudsman and has served as Senior Clinical Lecturer in England and Scotland, Academic Mentor, Undergraduate and Postgraduate educator.

Dr Kechagioglou has been awarded an MSc in Public Health/Health Management from the University of London and an MBA from Bradford University. She is currently working toward a Doctorate in Business Administration at Warwick Business School, researching the optimal Innovation adoption and diffusion model in the healthcare sector, by studying and comparing Innovation processes in the public and private healthcare organisations.

Dr. Ed Holupka

Edward J Holupka is Chief, Division of Medical Physics at Harvard Medical School and Assistant Professor of Radiation Oncology, Department of Radiation Oncology at Beth Israel Deaconess Medical Center. Following postdoctoral appointments at the University of Geneva and the Joint Center for Radiation Therapy, he was subsequently Chief of Treatment Planning at Harvard Medical School.

With a broad background in radiation oncology, including specific training and expertise in Imaging, his research includes ultrasound imaging for prostate cancer, image fusion, prostate radioactive seed therapy, and recently deep learning for medical imaging. His group was the first to publish a paper on intra-operative treatment planning for which he wrote and designed the software, licensed to Burdette Medical Systems (BMSI) and later to Elekta Medical Systems.


Dr. Marc Posner

Dr. Marc Posner serves as the Medical Director of the department of Radiation Oncology at Northwestern Lake Forest Hospital just north of Chicago. Originally from New York City, Dr. Posner is Harvard trained and has over 17 years’ experience practicing as a Radiation Oncologist. His internship was completed in the University of Chicago Hospital system, followed by residency at the University of California in San Francisco, serving as the Chief Resident in 1999.

Dr. Posner joined the Lake Forest Hospital staff in 2000. His special interests include highly conformal radiotherapy with IMRT, VMAT, and IGRT as well as stereotactic radiotherapy and radiosurgery (SBRT/SRS). He is an expert in the treatment of prostate cancer, as well as malignancies of the head and neck, gastrointestinal tract, breast, brain and lung, all of which are best approached with these newest radiation techniques. He has additional training and experience in the treatment of other cancers, and constantly works to improve outcomes and reduce side effects. He has lectured both nationally and internationally on the use of advanced radiotherapy techniques in the treatment of prostate, head and neck, breast, and other cancers.

He is happily married with twin children and twin dogs (a pair of pairs!).

Prof. Sir Michael Brady

Prof. Sir Michael Brady FRS, FREng, FMedSci is now Professor of Oncological Imaging in the Department of Oncology at the University of Oxford, having retired in 2010 as Professor of Information Engineering. He is co-Director of the Oxford Cancer Imaging Centre. He combines his work in oncology with a range of entrepreneurial activities. He is Deputy Chairman of Oxford Instruments plc. and also a founding director of successful startup companies such as Guidance and, of course, Mirada Medical. He was elected an Honorary Fellow of the IET and Institute of Physics. He was awarded the IEE Faraday Medal in 2000 and also the IEEE Third Millennium Medal for the UK. In 2005 the Royal Institution awarded Professor Sir Michael Brady the Henry Dale Prize for “outstanding work on a biological topic by means of an original multidisciplinary approach”.

Dr. Thomas Buchholz, M.D

Thomas Buchholz, M.D., is Medical Director of the Scripps MD Anderson Cancer Center – a comprehensive and clinically integrated cancer care program.  He holds the endowed Conrad Prebys Executive Medical Directors at Scripps.

As a radiation oncologist with a clinical focus on breast cancer, Dr. Buchholz has made significant scientific and academic contributions over the course of his career.  His research in the area of breast cancer has been published in more than 350 peer-reviewed journals.

Dr. Buchholz comes to San Diego after spending 20 years in Houston at The University of Texas MD Anderson Cancer Center where he held a variety of academic and executive leadership positions with MD Anderson, including division head and department chair of radiation oncology, and serving as Executive Vice President and Physician-in-Chief.