19th April 2013

Mirada Medical and Gray Institute Present Atlas-Based Contouring Study at ESTRO Meeting

Mirada Medical, in collaboration with the Gray Institute for Radiation Oncology and Biology, Oxford, UK, is presenting research at the annual European Society of Radiotherapy and Oncology (ESTRO) meeting, being held this week in Geneva, Switzerland. Titled “Methods for Assessing Atlas-based Contouring in Head and Neck Cancer”, the academic poster investigates which quantitative measures of the atlas-based auto-contouring of the head and neck correspond to a clinical assessment of quality. In doing so, this research addresses the question of how the clinical utility of auto-contouring can be assessed quantitatively. The poster has been nominated for the RTT Best Poster Award by ESTRO. The results of the study, to be presented in poster number PO-0946, indicate that while quantitative measures can be useful in assessing auto-contouring accuracy, there was not a best single measure for all structures investigated. For example, DICE worked well for the parotids but for others 2D contour errors were more appropriate. “Quantitative measures such as DICE coefficients are widely used to assess atlas-contouring technology yet there has been little to relate such scores to what really matters in a clinical setting”, commented Dr. Timor Kadir, Chief Science and Technology Officer at Mirada Medical, “We set out to investigate this connection with our collaborators as part of our on-going clinical validation of our technology and the results were surprising.” The same underlying atlas-contouring technology used in the research is being introduced in Mirada’s new Workflow Box and the latest version of RTx, their radiotherapy planning and assessment software solution. Mirada Workflow Box is a back-end server that performs automated atlas-based contouring and re-contouring for adaptive therapy and re-treatment. Planning CT images are transferred via DICOM to the Mirada Workflow Box, auto-contoured and forwarded to the TPS or Mirada Medical RTx workstation for checking and, if necessary, editing. Workflow Box requires no user interaction; therefore, reduces the time to perform such tasks and facilitates batch processing. Workflow Box and the RTx (v1.2) software suite will be demonstrated in the Mirada Medical stand (#5120) at ESTRO. Contributors to “Methods for Assessing Atlas-based Contouring in Head and Neck Cancer” will be available to discuss their poster.